Argentina scored twice in the first eight minutes but could not withstand Colombia's second-half pressure as the hosts rallied for a 2-2 draw in a thrilling World Cup qualifier on Tuesday.
Argentina coach Lionel Scaloni made five changes from the team that drew 1-1 with Chile last week and his side got the best possible start when Cristian Romero, playing in just his second international, headed home from a free kick inside three minutes.
Leandro Paredes made it 2-0 five minutes later when he dribbled through a pack of Colombian defenders and slipped the ball past the keeper.
Argentina controlled the first half but their dominance waned just before half-time after their goalkeeper Emiliano Martinez was taken off the field on a stretcher with a possible head injury following a goalmouth clash.
Argentina struggled to contain Colombia's Juan Cuadrado as the hosts started to create more opportunities, with Luis Muriel and Duvan Zapata both missing chances.
But they did get on the board five minutes into the second half after Argentine defender Nicolas Otamendi used an arm to flatten Mateus Uribe and Muriel converted the penalty.
Argentina too had chances but found Colombia goalkeeper David Ospina in inspired form, twice making great saves to thwart Lionel Messi.