The first Derby della Capitale of the season saw Lazio beat Roma 3-2 at the Stadio Olimpico on Sunday evening.
Sergej Milinkovic-Savic and Pedro Rodriguez found the back of the net to give the Biancocelesti a 2-0 lead after just 19 minutes, while Roger Ibanez was able to pull one back for the Giallorossi just before half time.
Felipe Anderson re-established Lazio's two-goal lead in the 63rd minute before Jordan Veretout converted a penalty six minutes later, with there being no more goals from this point on.
In a match-up that saw two new coaches face off in Maurizio Sarri and Jose Mourinho, it was Lazio that got off to the quicker start.
Just shy of the 10-minute mark in the match, Felipe Anderson floated cross into the area from a deep position that Milinkovic-Savic got to before Roma goalkeeper Rui Patricio to head into the back of the net.
Nine minutes later, Lazio doubled their lead. Roma had a penalty shout waved away and from the resulting counter-attack, Immobile carried the ball forward before teeing the ball up for Pedro to score against the club he left in the summer.
Nicolo Zaniolo had a good chance to cut the deficit to one goal in the 27th minute, but he saw his header come back out off the post after a teasing Jordan Veretout corner.